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Staff/Principal Engineer, Fluidics

Glyphic Biotechnologies

Glyphic Biotechnologies

Berkeley, CA, USA
Posted on Saturday, December 23, 2023

This is a full-time, exempt, on-site position based out of our Berkeley, CA office.

At Glyphic Biotechnologies, we plan to create the protein revolution for which scientists and researchers have been waiting. We are developing a massively parallel, single-molecule protein sequencing platform that will transform proteomics and usher in a new era of insights into human biology and disease. To date, we have raised >$20M from venture partners and non-dilutive grant funding to achieve our vision of next generation protein sequencing.

What we are looking for in you

Glyphic Bio seeks a Staff/Principal Engineer in Microfluidics and Mechanical Engineering to play a critical role in the development of Glyphic’s next generation protein sequencing platform. The candidate will be a primary stakeholder in the development of Glyphic’s sequencing technologies. The ideal candidate will have a strong background in product development for life science analytical systems that encompasses instruments, software, and system integration with reagents & consumables. Direct experience with proteomics and/or NGS strongly preferred.

Primary Responsibilities

  • Lead the development of fluidic systems for Glyphic’s sequencing technologies and products.

  • Design and develop micro-fluidic devices for breadboard and prototype instruments.

  • Contribute to reagent and process development for R&D projects.

  • Evaluate and manage collaborations with external vendors for product development.

  • Collaborate with Product Development and R&D team members to direct product development.

  • Allocate and coordinate engineering team resources (internally and externally with vendors).

Required Competencies

  • Ph.D. or M.S. in engineering, physics, bioengineering, or a related field.

    • For Staff Engineer: Ph.D with 8+ years of industry experience; or M.S. with 12+ years of post-graduate experience.

    • For Principal Engineer: Ph.D with 12+ years of industry experience; or M.S. with 16+ years of post-graduate experience.

  • Previous involvement in the development of a robust, high-quality instrument-based platform for life sciences that has achieved commercial success.

  • Expertise in fluidics simulation and design using relevant software (e.g., Fluent, ANSYS, Solidworks, and COMSOL).

  • A history of working productively with intellectually diverse teams across R&D and Product Development.

  • Experience in establishing and managing external collaborations and vendor relationships.

  • Exceptional communication skills, with the ability to communicate rationale of pipeline design and clear visualization of results.

  • A tendency toward being hyper-organized.

  • Ability to work with multiple teams and maintain several projects in parallel.

  • Ability to work independently with limited oversight.

  • A commitment to maintaining the highest levels of workplace professionalism.

  • A willingness to self-start, embrace ambiguity and seek out opportunities for company, team, and individual improvement.

Preferred Qualifications

  • Experience developing liquid handling platforms for NGS sample preparation

  • Demonstrated success with magnetic bead handling for life science applications

  • Experience developing modules for DNA/Peptide synthesizers, Edman degradation instruments, and instruments related to proteomics and DNA analysis

Physical/Cognitive Requirements

  • Prompt and regular attendance, punctuality, and availability to work at assigned work location, including adhering to the Department’s attendance policy (e.g., adhering to your work schedule, including but not limited to: scheduled tasks, meetings, meal/rest breaks, etc.).

  • Ability to work shifts of at least 8 hours, 5 days per week.

  • Ability to work from a dedicated space that is distraction-free and has a secure, high-speed, internet connection.

  • Ability to thrive in a fast-paced, high-intensity work environment.

  • Ability to remain seated in a stationary position for prolonged periods.

  • Requires eye-hand coordination and manual dexterity sufficient to operate keyboard, computer, and other standard laboratory and facilities equipment.

  • No heavy lifting is expected, though occasional exertion of about 20 lbs. of force may be required.

  • Ability to interact with leadership, employees, and members in an appropriate and respectful manner.

  • Maintains composure during moments of stress, maintains a helpful disposition at all times, and leverages de-escalation skills and techniques when necessary.

  • Ability to exercise good judgment, work effectively under time constraints, prioritize work, multi-task, and adapt to changing work demands.

Not sure you meet 100% of our qualifications?

We encourage anyone who thinks they would excel at Glyphic Bio to apply, no matter their background or how they identify.

Benefits and Perks

  • 100% Coverage for Employees & Dependents on a Comprehensive Health Plan (Medical, Dental, & Vision)

  • Employer Retirement Contributions // 401(k)

  • Employee Stock Option Plan

  • Unlimited Paid Time Off // Vacation, Sick, & Public Holidays

  • Commuter Transportation Subsidy // Public Transit & Parking

  • Paid Maternity and Paternity Leave

  • Coverage for Skill Training & Development Courses

  • Office Workstation Stipend

  • Health & Wellbeing Stipend towards Gympass Access

  • Free Coffee and Snacks in the Office

We are an Equal Opportunity Employer. We celebrate diversity and are committed to creating an inclusive environment for all employees. Individuals seeking employment at Glyphic Biotechnologies are considered without regard to race, color, religion, national origin, age, sex, marital status, ancestry, physical or mental disability, veteran status, gender identity, or sexual orientation. We require that all employees be fully vaccinated against COVID-19 and provide proof thereof or receive an approved medical or religious exemption.